Novartis provides update on use and safety of Beovu® in patients with wet AMD

March 11, 2020

Patient safety is at the heart of everything we do. Whenever adverse events are reported, we take them seriously and investigate them thoroughly. 

As previously shared, our global safety organization is conducting a comprehensive review of a limited number of events reported as severe vision loss, retinal artery occlusion and/or vasculitis in patients treated with Beovu, including cases where patients had previously received other VEGF inhibitors. 

To date, the data continue to support an overall favorable benefit-risk profile for …

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Sandoz Resolves Generic Drug Antitrust Investigation in the U.S.

Princeton, New Jersey, March 2, 2020 – Sandoz Inc. has reached a resolution with the U.S. Department of Justice (DOJ) Antitrust Division concerning the Department’s more than three-year-long antitrust investigation into the U.S. generic drug industry. The Sandoz resolution relates to instances of misconduct at the company between 2013 and 2015 with regard to certain generic drugs sold in the United States. As part of the resolution, Sandoz has agreed to pay USD 195 million and will enter into a deferred prosecution agreement (DPA).

Sandoz is a global leader in generic …

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Novartis shareholders approve all resolutions proposed by the Board of Directors at the Annual General Meeting

  • Shareholders approve 23rd consecutive dividend increase to CHF 2.95 (+4%) per share for 2019; representing a 3.5%1 yield and approximately 54% payout of free cash flow
     
  • Shareholders confirm Dr. Joerg Reinhardt as Chairman of the Board of Directors as well as all other members who stood for re-election; Ms. Bridgette Heller and Mr. Simon Moroney elected to the Board of Directors
     
  • Shareholders approve all other proposals of the Board of Directors, including the 2019 Compensation Report in an advisory …
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Sandoz commits to keep prices stable for basket of essential COVID-19 medicines; Novartis responds to COVID-19 with broad range of initiatives

Sandoz, a global generics leader and the #1 provider of off-patent antibiotic medicines worldwide, is making a public commitment to ensure stable pricing for a basket of essential medicines the company markets, which may help to treat coronavirus patients, amid growing concerns about the potential impact of the coronavirus outbreak on global supply chains.

Richard Saynor, Sandoz CEO, says: “I am very concerned about reports that prices for basic medicines such as painkillers and antibiotics are rising substantially as a result of a tightening supply situation for active …

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Parental Leave at Novartis: Alfred’s story

At Novartis, we celebrate life and recognize moments that matter. One of the most life-changing moments our associates experience is becoming a parent and welcoming new life into their lives. In July 2019, we introduced equal paid parental leave of at least 14 weeks to all parents, regardless of gender. We believe that this will empower our people to make the right choices for the health and well-being of their families, by enjoying more flexibility and financial stability, at the times when it matters the most.

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Novartis and DNDi to collaborate on the development of a new oral drug to treat visceral leishmaniasis

  • LXE408 is a first-in-class compound, discovered at Novartis with financial support from the Wellcome Trust
     
  • Novartis is responsible for completing Phase I clinical trials and has committed to maximizing access in endemic countries, once approved
     
  • DNDi will lead Phase II and III clinical development, starting in India with additional trials planned in East Africa
     
  • Leishmaniasis, which is transmitted by the sand fly, affects over one billion people; visceral leishmaniasis, the most serious form of the …
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Shaping the future of sickle cell disease

Majara, a 32-year-old woman from Greenville, North Carolina, in the US, vividly remembers the times when her sickle cell pain crises gripped her body so badly she couldn’t move. “It felt like a dump truck had actually fallen on my body and was just sitting there… Stabbing. I ached all over. There were times where I just wanted the doctor to take away whatever part of my body was hurting,” Majara recounts.

Majara lives with sickle cell disease –a complex and debilitating, genetic blood disorder that goes beyond sickle-shaped red blood cells. The disease is associated with chronic …

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Novartis announces FDA and EMA filing acceptance of ofatumumab, a novel B-cell therapy for patients with relapsing forms of multiple sclerosis (RMS)

  • Filings are supported by Phase III ASCLEPIOS I and II studies, where ofatumumab showed highly significant and clinically meaningful reduction in the number of confirmed relapses, evaluated as annualized relapse rate (ARR)1
     
  • Ofatumumab is a novel B-cell therapy that delivers sustained efficacy with a favorable safety profile1
     
  • If approved, ofatumumab has the potential to become a first-choice treatment for a broad RMS population and the first B-cell therapy that can be self-administered at home …
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Collaboration is strengthening care for chronic illness in Ethiopia

For Kassahun, a used clothing merchant in Ethiopia, managing his diabetes is something of an obstacle course. In the rural area where he lives, there are no doctors specialized in treating the disease, which if poorly managed can spark a host of other health problems, including heart disease, vision problems and nerve damage. So Kassahun travels 300 kilometers (approximately 186 miles) by public transportation to the capital Addis Ababa to see a specialist at the Black Lion Hospital, requiring him to spend several nights in a hotel.

“If we had more skilled physicians in the regions, …

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Novartis receives EC Approval for Beovu®, a next-generation anti-VEGF treatment for wet AMD, a leading cause of blindness worldwide

  • Beovu (brolucizumab) is the only anti-VEGF treatment approved in Europe for wet AMD that offers the option to start eligible patients on three-month dosing intervals immediately after the loading phase1
     
  • For the more than 20 million people worldwide who are living with wet AMD, frequent injections are a common reason patients drop off existing treatments2-4
     
  • Approval is based on two head-to-head clinical trials, HAWK and HARRIER, in which Beovu achieved robust vision gains that were …
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